Synthesis of 1,5-triazole bridged vancomycin CDE-ring bicyclic mimics using RuAAC macrocyclization.
نویسندگان
چکیده
Herein we report the Ru(II)-catalyzed double-macrocyclization of a hexapeptide to obtain a mimic of the bicyclic CDE-ring of vancomycin, followed by measurement of its binding affinity for small peptide ligands using ITC.
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عنوان ژورنال:
- Chemical communications
دوره 49 40 شماره
صفحات -
تاریخ انتشار 2013